(S)-Benzyl 3-phenyl­carbamoyl-1,2,3,4-tetra­hydro­isoquinoline-2-carboxyl­ate

نویسندگان

  • Tricia Naicker
  • Madichaba Chelopo
  • Thavendran Govender
  • Hendrick G. Kruger
  • Glenn E. M. Maguire
چکیده

There are two independent mol-ecules in the asymmetric unit of the title compound, C(24)H(22)N(2)O(3). The heterocyclic ring assumes a twisted boat conformation and N-H⋯O inter-actions help to construct the three-dimensional network within the crystal packing.

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منابع مشابه

(1S,3S)-Methyl 2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carboxyl­ate

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(S)-Methyl 2-[(3R,4R)-2-benzyl-3-(2-fur­yl)-1-oxo-1,2,3,4-tetra­hydro­isoquinoline-4-carboxamido]-3-(1H-indol-3-yl)propanoate

The title compound, C(33)H(29)N(3)O(5), was synthesized by the reaction of racemic trans-2-benzyl-3-(2-fur-yl)-1-oxo-1,2,3,4-tetra-hydro-isoquinoline-4-carboxylic acid, l-tryptophan methyl ester and diisopropylcarbodiimide in dry dichloro-methane. The furan ring is disordered over two positions in a 0.859 (14):0.141 (14) ratio. In the 1,2,3,4-tetra-hydro-iso-quin-oline ring system, the heterocy...

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(S)-N-Benzyl-2-methyl-1,2,3,4-tetra­hydro­isoquinoline-3-carboxamide

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(S)-2-Benzyl-N-(2,6-diisopropyl­phen­yl)-1,2,3,4-tetra­hydro­isoquinoline-3-carboxamide

The asymmetric unit of the title compound, C(29)H(34)N(2)O, contains two mol-ecules in which the N-containing six-membered rings assume different conformations viz. half-chair and envelope. Inter-molecular N-H⋯O hydrogen bonding via the amide groups cross-link the mol-ecules in the crystal structure.

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عنوان ژورنال:

دوره 68  شماره 

صفحات  -

تاریخ انتشار 2012